Although you may not feel anything different right after getting your first HGH injection, your plasma GH levels will start increasing within minutes and reach a peak within 3-4 hours. HGH injections have a half-life of 7-9 hours when taken subcutaneously and your GH levels will return back to their baseline levels within 12 hours of the injection.
That’s why it is recommended to receive daily injections with HGH. This way your therapy will also mimic the natural daily release of growth hormone by the pituitary gland.
Younger individuals appear to be less sensitive to the effects of growth hormone, so the effectiveness of the therapy will depend on your age. Studies reveal older adults tend to require lower doses to achieve the same improvements in their condition when compared to younger individuals.
The main benefit of HGH injections is the fact that the medication can help manage all the symptoms of GHD, including chronic fatigue and weight gain.
HGH therapy can help patients lose extra body fat, increase their lean muscle mass, improve their energy levels, support the quality of their sleep, and boost their mood, overall health, and quality of life.
The downsides of the therapy include the risk of local reactions around the injection site such as pain, redness, and swelling. Taking large doses of HGH can also lead to side effects such as water retention and reduced insulin sensitivity.
HGH can stimulate cell division, so the therapy is contraindicated in patients with oncological conditions as it may stimulate tumor cells as well.
Currently, all FDA-approved brands of HGH appear to be equally effective for stimulating muscle protein synthesis, increasing lean mass, and body fat loss.